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What side effects may occur?
Oral: (GI side effects reduced if take with meals)
Short-term therapy: nausea/vomiting, diarrhea, headache, dizziness, fatigue, skin rash, edema. inguinal adenopahty, anorexia, leg pain, medicatio n taste, sore throat.
Long-term: nausea/vomiting, diarrhea, headache, vertigo, insomina, irritability, depression, skin rash, acne. accelerated hair loss, arthralgia, fever, palpitations, sore thr oat, muscle cramps, mestrual abnormalities, lyphadenopathy.

Other medical problems
This medication should be used cautiously during pregnancy only if clearly needed. It is not known if this medication appears in breast milk. Consult with your doctor before breast-feeding.
Avoid s exual activity while signs and symptoms of genital herpes are present to prevent infecting your partner. Inform your doctor if this medication does not appear to decrease the frequency or severity of recurrent infections.

How should this medicine be used?
Begin taking this medication as soon as symptoms appear. Take this medication as directed. Ask your doctor or pharmacist if you have any questions. Try to take the medication at evenly spaced interval s throughout the day and night. This will ensure a constant blood level of the medication and is most effective.

Possible food and drug interactions when taking this medication
It is especially important that your health care professional know if you are taking any of the following:
- Carmustine (e.g., BiCNU) or
- Cisplatin (e.g., Platinol) or
- Combination pa in medicine containing acetaminophen and aspirin (e.g., Excedrin) or other salicylates or
- Cyclosporine (e.g., Sandimmune) or
- Deferoxamine (e.g., Desferal) (with long-term use) or
- Gold salts (medicine for arthritis) or
- Inflammation or pain medicine, except narcotics, or
- Lithium (e.g., Lithane) or
- Methotrexate (Mexate) or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine) or
- Plicamycin (e.g., Mithracin) or

Symptoms of overdose may include:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness, or se izures.

Precautions while Using this Medicine
If you are or may be pregnant, check with your doctor for instructions on using this medicine during pregnancy.


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